Papaverine carbanion and its preparation

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 217/20 (2006.01)

Patent

CA 1152997

ABSTRACT OF THE DISCLOSURE The invention relates to the carbanion of 1-(3,4- dimethoxy-benzyl)-6,7-dimethoxy-isoquinoline which can be readily converted to the novel 1-[1-(3,4-dimethoxy-phenyl)-3- oxo-propyl]-6,7-dimethoxy-isoquinoline which is a useful intermediate in preparing the novel 1-[1-(3,4-dimethoxy- phenyl)-3-amino or amino substituted-propyl]-6,7-dimethoxy- isoquinoline which are useful in the cardiac and vascular fields.

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