Process for the preparation of nucleosides

Details Process for the preparation of nucleosides Process for the preparation of nucleosides

C - Chemistry, Metallurgy

07

H

260/229, 195/1.1

C07H 19/04 (2006.01)

Patent

CA 1107277

ABSTRACT OF THE DISCLOSURE The present invention provides a proccss for the preparation of a nucleoside from a nucleoside base and a 1-o-acyl or 1-halogen derivative of a protected mono-, oligo- or poly- saccharide or a 2-o-acyl, 2-o-alkyl or 2-halogen derivative of tetrahydrofuran or tetrahydropyran, wherein reaction is carried out in one step in the presence of a catalyst and silylation reagent.

318170

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