Process for the preparation of...

C - Chemistry – Metallurgy – 07 – D

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C07D 233/22 (2006.01) C07D 233/50 (2006.01)

Patent

CA 1062267

PROCESS FOR THE PREPARATION OF 1-BENZOYL-2-(2',6'- DICHLOROPHENYLAMINO)-2-IMIDAZOLINE AND SALTS THEREOF ABSTRACT OF THE DISCLOSURE A process for the preparation of 1-berzoyl-2- (2',6'-dichlorophenylamino)-2-imidazoline or a salt thereof, which comprises reacting a 2,6-dichlorophenyl- isocyanide dihalide with benzoylethylenediamine in a solvent inert to the reactants at a temperature from 0°C. up to the boiling point of the solvent used, preferably from +10°C. to +50°C., in the presence of an acid- binding agent, and isolating the desired product as the free base or a salt with an inorganic or organic acid.

259993

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