B - Operations – Transporting – 01 – D
Patent
B - Operations, Transporting
01
D
167/322, 161/35
B01D 9/04 (2006.01) A01N 1/02 (2006.01) A61K 8/04 (2006.01) A61K 8/11 (2006.01) A61K 9/19 (2006.01) A61K 9/20 (2006.01) A61Q 19/00 (2006.01) F26B 5/06 (2006.01)
Patent
CA 1097209
ABSTRACT OF THE DISCLOSURE The process produces pharmaceutical, cosmetic or diagnostic formulations by the freeze drying of one or more substances in solution or in suspension in a solvent or a mixture of solvents. The solution or suspension is locally and progressively cooled in a controlled manner while agitating so as to produce microcrystals of solvent which are put in suspension in the remainder of the liquid until there is obtained a high-viscosity microcrystalline complex system comprising essentially isolated microcrystals of solvent in intimate mixture with interstitial liquid phases having a high concentration of the initially present substances. The microcrystalline complex system is hardened by cooling and lyophilized. This process permits the obtainment of lyophilized formulations having a higher dissolving or dispersing rate and lyophilized compositions of normally incompatible substances. - 1 -
311409
Goudreau Gage & Associates
Laboratoire L. Lafon
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