Pharmaceutical compositions containing paracetamol

A - Human Necessities – 61 – K

Patent

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167/149

A61K 31/375 (2006.01) A61K 9/50 (2006.01) A61K 31/16 (2006.01)

Patent

CA 1157376

Abstract Pharmaceutical Compositions containing Paracetamol The acute liver toxicity effects of paracetamol are reduced by co-formulating with sustained release ascorbic acid which produces high liver concentrations of ascorbate anion after oral administration of the co-formulation. A suitable form of sustained release ascorbic acid is prepared by microencapsulation of particles of ascorbic acid in membranes which act as microdialysis cells.

360190

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