Biologically active amides

Details Biologically active amides Biologically active amides

C - Chemistry, Metallurgy

07

C

260/552

C07C 69/76 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01)

Patent

CA 1075714

ABSTRACT Compound of formula (I) Image (I) wherein X is chlorine, bromine or iodine and R is hydrogen or alkyl having 1 to 3 carbon atoms, have anti-convulsant activity in mammals in established pharmacological tests. All compounds of formula (I) are novel with the exception of that wherein X is chlorine and R is hydrogen. Provided are pharmaceutical compositions comprising a compound of formula (I) together with an acceptable carrier therefor, and the use of the compounds in medicine. Also provided are the novel compounds as above defined and methods for their synthesis.

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