Production of penicillins

Details Production of penicillins Production of penicillins

Category

C - Chemistry, Metallurgy

Subcategory

07

Subsubcategory

D

CPC

260/113

IPC codes

C07D 499/44 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01)

Type

Patent

Patent number

CA 1141752

Description

-49- III. Abstract: Trimethylsilyl or another easily hydrolyzed ester of 6-trimethylsilyloxycarbonylaminopenicillanic acid was prepared by bubbling dry carbon dioxide into an anhydrous solution of the corresponding 6-trimethyl- silylaminopenicillanate and found to be a useful inter- mediate in the production of penicillins, e.g., amoxicillin and ampicillin, by its acylation in anhydrous media with the appropriate acid chloride or acid chloride hydrochloride.

Application Number

328553

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