Thioxopyrazolo[1,5-c]quinazoline derivatives and related...

Details Thioxopyrazolo[1,5-c]quinazoline derivatives and related... Thioxopyrazolo[1,5-c]quinazoline derivatives and related...

C - Chemistry, Metallurgy

07

D

260/242.01

C07D 487/04 (2006.01)

Patent

CA 1111033

Abstract THIOXOPYRAZOLO[1,5-c]QUINAZOLINE DERIVATIVES AND RELATED COMPOUNDS New compounds, useful as anti-allergics, have the structure Image wherein R1 is hydrogen or lower alkyl; R2 is carboxyl, hydroxymethyl, lower alkanoyloxymethyl or lower alkoxy- carbonyl; R3 is hydrogen, lower alkyl or benzyl; R4 and R5 are the same or different and are selected from hydrogen, alkyl of 1 to 4 carbons, alkoxy of 1 to 4 carbons, hydroxy, lower alkanoyloxy of 1 to 4 carbons, nitro, halogen, trifluoromethyl, benzyloxy, or benzyloxy having a lower alkoxy, halogen, hydroxy, nitro, or trifluoro- methyl substituent; and physiologically acceptable salts thereof.

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