Phenylalkanols and a process for their preparation

C - Chemistry – Metallurgy – 07 – C

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260/627.1, 260/5

C07C 33/18 (2006.01) C07C 43/20 (2006.01) C07C 43/295 (2006.01)

Patent

CA 1077962

ABSTRACT OF THE DISCLOSURE Novel phenylalkanols are provided herein of the formula Image wherein Ar is phenyl or phenyl monosubstituted or disubstituted by F, C1, Br and/or CH3, X is F, C1, Br, or in one preferred embodiment, C -N, m is O or 1, and n is 2 or 3. These phenylalkanols possess antiinflammatory activity. They can preferably be produced by treating a compound of formula Image wherein Q is a functionally modified hydroxy group and Ar, X, m and n have the values given above, with a solvolyzing agent.

251509

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