Glucose detection system free from fluoride-ion interference

Details Glucose detection system free from fluoride-ion interference Glucose detection system free from fluoride-ion interference

G - Physics

01

N

150/2

G01N 33/66 (2006.01) C12Q 1/54 (2006.01) G01N 21/00 (2006.01)

Patent

CA 1114723

IMPROVED GLUCOSE DETECTION SYSTEM FREE FROM FLUORIDE-ION INTERFERENCE Abstract of the Disclosure An improved multilayer element for detecting glucose in samples of biological fluid which may contain with fluoride ion as a contaminant or preservative is described. The improved element comprises a buffered Trinder's reagent, which reagent comprises glucose oxidase, peroxidase, 4-aminoantipyrine and a phenolic or naphtholic coupler, which is buffered to a pH between about 4.5 and about 6Ø Such a buffering reduces any interference which may be due to fluoride ion present in the sample under analysis.

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