Process for the synthesis of 3',4'-dideoxykanamycin b

Details Process for the synthesis of 3',4'-dideoxykanamycin b Process for the synthesis of 3',4'-dideoxykanamycin b

C - Chemistry, Metallurgy

07

H

260/230.5

C07H 15/22 (2006.01) C07H 15/236 (2006.01)

Patent

CA 1075684

TITLE OF INVENTION: New process for the synthesis of 3',4'- dideoxykanamycin B. ABSTRACT OF THE DISCLOSURE: A useful antibiotic, 3',4'-dideoxykanamycin B can be prepared in shortened steps and in an improved overall yield by a new process starting form kanamycin B via new intermediate derivatives of kanamycin B in which all the amino groups and possibly the 2"-hydroxyl group are protected with sulfonyl-type protecting groups selected from lower alkyl-, aryl- and aralkyl-sulfonyl groups. - 1 -

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