Stabilized peroxidase reagent for enzyme immunoassay

C - Chemistry – Metallurgy – 12 – Q

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167/45, 195/33.1

C12Q 1/28 (2006.01) A61K 38/44 (2006.01) C12N 9/96 (2006.01)

Patent

CA 1098824

Abstract of the Disclosure A new and useful stable peroxidase compositions are disclosed which are particularly useful as reagents in enzyme immunoassay (EIA) tests for the determination of a component of the antigen-antibody reaction. The novel peroxidase compositions contain polyvalent ions of periods 3 and 4 of the Periodic Table which are metals in Groups IIA, IIIB, IVB, VB, VIB, VIIB, VIII, IB, IIB and IIIA. These novel compositions are stable even in low concen- trations, and are relatively invulnerable to freeze-drying. Preferably, the polyvalent ions selected are those of Al, Zn, Mg, Fe, and Cu.

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