Preparation of albumin

A - Human Necessities – 61 – K

Patent

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530/15.06

A61K 35/16 (2006.01)

Patent

CA 1116515

ABSTRACT OF THE DISCLOSURE The present invention provides a method for the prepara- tion of albumin comprising: (a) adjusting the pH of plasma in liquid form to about 6.7; (b) heating the plasma at a temperature of approximate- ly 60°C for about 1 1/2 hours; (c) adjusting the pH of -the plasma to about 5.7; (d) precipitating impurities from the plasma by the addition of ethanol in an amount sufficient to give a final concentration of about 40 to 44% in the plasma along with cooling of the plasma to about -5°C, with the albumin remaining in the supernatant; and (e) precipitating albumin from said supernatant at a pH of about 4.8.

376748

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