Diagnostic test

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G - Physics

01

N

167/37

G01N 33/569 (2006.01) G01N 33/543 (2006.01)

Patent

CA 1138331

ABSTRACT OF THE DISCLOSURE A highly sensitive direct particle agglutination test capable of routinely detecting as little as 0.2 nanograms of antigen per milliliter of clinical fluid and characterized by uniform sensitivity as well as stability is disclosed as well as coated particles having a sentitivity of 0.2 nanograms antigen per milliliter and methods for preparing such coated particles. In addition, a method to reduce the frequency of non-specific agglutination with human sera to 2% or less is described.

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