Phenacyl-type esters of pgf and process

C - Chemistry – Metallurgy – 07 – C

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260/235.03

C07C 405/00 (2006.01)

Patent

CA 1076570

ABSTRACT OF THE DISCLOSURE Phenacyl-type esters of PGF2.alpha., 15(S)-15-methyl-P6F2.alpha.. and 15(R)-15-methyl-PGF2.alpha. are disclosed, represented by the formula Image wherein M is Image , Image , or Image ; wherein R1 is phenyl, p-bromophenyl, p-biphenylyl, p-nitro- phenyl, p-benzamidophenyl, or 2-naphthyl; and wherein R2 is hydrogen or benzoyl. The products are useful for the same pharmacological and medical purposes as the corresponding prostaglandin and analogs, and are also useful as a means for obtaining highly purified products. - 1 -

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