C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/105.1
C07D 501/30 (2006.01) A61K 31/545 (2006.01) C07D 205/08 (2006.01) C07D 213/56 (2006.01) C07D 213/89 (2006.01) C07D 249/02 (2006.01) C07D 257/04 (2006.01) C07D 261/10 (2006.01) C07D 271/02 (2006.01) C07D 275/02 (2006.01) C07D 279/06 (2006.01) C07D 285/04 (2006.01) C07D 307/54 (2006.01) C07D 501/04 (2006.01) C07D 501/20 (2006.01) C07D 501/36 (2006.01) C07F 7/08 (2006.01) C07F 7/22 (2006.01)
Patent
CA 1056815
ABSTRACT This invention relates to new three-thio derivatives of thio- alkoxycarbonyl-and carbamoyl-substituted thioacetylcephalo- sporins of the formula Image wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, tri(lower alkyl)silyl, a salt forming ion, or the group -CH2-O-?-R4 and in addition, tri(lower alkyl)stannyl and phenyl when R? is lower alkylthio; R1 is hydrogen, lower alkyl, phenyl, thienyl, furyl or pyridyl; R? is lower alkyl- thio, lower alkylamino or phenyl-lower alkylamino; R3 is lower alkylthio or a 5-membered heterocycle containing only nitrogen and carbon or nitrogen, carbon and sulfur in the ring when R? is lower alkylthio, and when R? is lower alkyl- amino or phenyl-lower alkylamino, R3 is a five or six membered nitrogen, sulfur and/or oxygen containing ring system; and R4 is lower alkyl, phenyl or phenyl-lower alkyl; are useful as antibacterial agents.
223673
Breuer Hermann
Treuner Uwe D.
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