Diphenylalkanoether and diphenylalkanone oximeether derivatives

Details Diphenylalkanoether and diphenylalkanone oximeether derivatives Diphenylalkanoether and diphenylalkanone oximeether derivatives

C - Chemistry, Metallurgy

07

D

260/392, 260/557

C07D 295/08 (2006.01) C07D 213/30 (2006.01) C07D 295/088 (2006.01) C07D 307/42 (2006.01) C07D 333/16 (2006.01)

Patent

CA 1126747

ABSTRACT The invention comprises diphenylalkanoether and diphenylalkanone oxime-ether derivatives of the formula: Image wherein R1 and R2 are each independently an aryl group optionally substituted with 1 to 3 substituents selected from the group consisting of halogen, C1-C4 alkyl, C1-C4 alkoxy, nitro, cyano, di(C1-C4)alkylamino, amino, benzyloxy, hydroxyl, C1-C4 alkylthio, C1-C4 alkylsulfinyl, C1-C4 alkysulfonyl, C1-C4 alkanoylamino, C1-C4 alkylamino and N- (C1-C4)alkyl-N-(C1-C4)alkanoylamino, Z1 is a group of the formula: Image (wherein R3 and R4 are each independently a hydrogen atom, a C1-C4 alkyl group or an ar(C1-C4)alkyl group or, when taken together with the adjacent notrogen atom to which they are attached, represent a nitrogen-containing 5 to 7-membered saturated heterocyclic group optionally having an oxygen atom or an additional nitrogen atom as the hetero atom in addition to the said nitrogen atom and, in case of having the additional nitrogen atom, bearing a hydrogen atom, a C1- C4 alkyl group, an ar(C1-C4)alkyl group or a phenyl group thereon), -?- is a group of the formula: -?- or the formula: -?H-, A1 is a C2-C6 alkylene group and A is a C2-C4 alkylene group, and non-toxic, pharmaceutically acceptable acid addition salts thereof. These compounds have cerebral vasodilating activity and antihypoxic activity, and are therefore valuable pharmaceuticals.

349064

Affiliated with

Also associated with

Rating

Diphenylalkanoether and diphenylalkanone oximeether derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Diphenylalkanoether and diphenylalkanone oximeether derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diphenylalkanoether and diphenylalkanone oximeether derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-313784