Amino derivatives of pyrido (3,4-b) pyrazine carboxylic...

Details Amino derivatives of pyrido (3,4-b) pyrazine carboxylic... Amino derivatives of pyrido (3,4-b) pyrazine carboxylic...

C - Chemistry, Metallurgy

07

D

260/265.3

C07D 471/04 (2006.01) C07D 213/80 (2006.01)

Patent

CA 1036605

ABSTRACT New derivatives of pyrido[3,4-b]pyrazine carboxylic acids and esters and their acid addition salts, useful as anti-inflammatory agents and central nervous system depressants, have the general formula Image wherein R, R3, R4 and R5 each is hydrogen or lower alkyl; R1 and R2 each is hydrogen, lower alkyl, lower alkanoyl, di(lower alkylamino)lower alkyl, or Image is an unsubstituted or substituted heterocyclic of the group consisting of piperidinyl, and piperazinyl; wherein the substituted heterocyclic bears a hydroxy-lower alkyl, one or two loweralkyl or a phenyl group.

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