Indolopyrones having antiallergic activity

C - Chemistry – Metallurgy – 07 – D

Patent

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260/298.5

C07D 491/04 (2006.01)

Patent

CA 1110249

ABSTRACT OF THE DISCLOSURE The invention relates to novel substituted indolo- pyrones of the general formula: Image wherein R1 and R2 may be hydrogen, hydroxy, lower alkoxy or lower alkyl of 1 to 6 carbon atoms, halogen, trifluoromethyl, nitro, or may be taken together to form a methylenedioxy group. R3 may be hydrogen, lower alkyl of 1 to 6 carbon atoms, aryl (such as phenyl), or substituted aryl. R4 may be carboxamido, cyano, or tetrazolyl. These compounds possess antiasthmatic and antiallergic properties.

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