Meta-sulfonamido-benzamide derivatives

Details Meta-sulfonamido-benzamide derivatives Meta-sulfonamido-benzamide derivatives

C - Chemistry, Metallurgy

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C07D 207/08 (2006.01) C07D 207/09 (2006.01) C07D 207/14 (2006.01) C07D 307/14 (2006.01)

Patent

CA 1085411

META-SULFONAMIDO-BENZAMIDE DERIVATIVES ABSTRACT Meta-sulfonamido-benzamide derivatives of the formula: Image [wherein R is a hydrogen atom or a lower alkyl, cyano, or lower alkane- sulfonyl group; R1 is a lower alkyl, phenyl, amino, lower alkylamino, di(lower)- alkylamino, or C4 - C5 alkyleneamino group, R2 is a hydrogen or halogen atom or a lower alkyl, di(lower)alkyl- amino, or lower alkoxy group; R3 is a hydrogen atom or a methyl or methoxy group, R4 is a hydrogen or halogen atom, R5 is a lower alkyl, lower alkenyl, C3 - C6 cycloalkyl, benzyl, or halogenobenzyl group, and n is 1 or zero] or their acid addition salts, showing pharmacological activity such as anti-emetic or psychotropic activity, are provided via several routes.

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