Arylmalonamido-1-oxadethiacephalosporins

Details Arylmalonamido-1-oxadethiacephalosporins Arylmalonamido-1-oxadethiacephalosporins

C - Chemistry, Metallurgy

07

D

260/244.2

C07D 498/04 (2006.01) A61K 31/535 (2006.01) C07D 205/00 (2006.01) C07D 265/00 (2006.01) C07D 505/00 (2006.01)

Patent

CA 1085392

ARYLMALONAMIDO-1-OXADETHIACEPHALOSPORINS ABSTRACT Antibacterial 1-oxadethiacephalosporins of the formula: Image [where Ar is Image , Image , Image , Image , or Image (in which Acyl is organic or inorganic acyl); COB1 and COB2 each is carboxy or protected carboxy; Het is Image , Image , or Image (in which COB3 is carboxy or protec- ted carboxy); and Y is hydrogen or methoxy; with proviso that when Y is methoxy, Het is Image ], the preparation and use of them are disclosed.

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