Process for the production of unsaturated or substituted...

Details Process for the production of unsaturated or substituted... Process for the production of unsaturated or substituted...

C - Chemistry, Metallurgy

07

H

260/228, 260/233

C07H 13/10 (2006.01) C07H 19/01 (2006.01)

Patent

CA 1114813

Case 4-10690/+ CANADA PROCESS FOR THE PRODUCTION OF UNSATURATED OR SUBSTITUTED METHYL ETHERS HAVING ANTIBIOTIC ACTION Abstract of the Disclosure The antibiotics Papulacandin A and Papulacandin B are etherified at the phenolic groups in positions 10 and/or 12 by introducing a group -CH2-K wherein K is a hydrocarbon radical which is either un- saturated and aliphatic, or it is saturated or unsaturated and substituted by cyclic hydrocarbons, such as aromatic or heterocyclic ones, or by functional groups, such as halogens, carboxyl groups, carboxyl ester or amide groups. These ethers are characterized by a good antifungal action e.g. against Candida albicans and also by an antifiral action.

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