C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/242.01
C07D 487/04 (2006.01)
Patent
CA 1137474
Abstract The known blood platelet antiaggregative agent 6,7-dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)- one is prepared in high yield via an improved process involving a novel intermediate of the Formula Image III in which R1 is (lower)alkyl and X is bromo, chloro, or iodo. The intermediate is converted to the final product by reaction with about an equimolar amount of a base in a non-reactive solvent.
381570
Beverung Warren N.
Jenks Thomas A.
Partyka Richard A.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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