Immunoassay using magnetically attractable particles

G - Physics – 01 – N

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G01N 33/53 (2006.01) B01J 20/28 (2006.01) G01N 33/50 (2006.01) G01N 33/543 (2006.01)

Patent

CA 1112161

ABSTRACT A method of immunoassay of a liquid sample in which a reaction mixture is formed and one or more components of the mixture are selectively removed by contacting the mixture with a particulate reagent comprising a polymeric matrix having a selective absor- bent material and magnetic particles incorporated therein. By applying a magnetic field, the particulate reagent can be separated from the mixture. The same particulate reagent may be used in a series of immuno- assays for different constituents of interest in liquid samples. The method may be effected by discrete manual techniques or by automated continuous flow analysis. The particulate reagents and their method of production constitute a further aspect of the invention. - 1 -

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