Selective conversion of 20-methyl-pregna-...

C - Chemistry – Metallurgy – 07 – J

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260/97

C07J 7/00 (2006.01) C07J 9/00 (2006.01)

Patent

CA 1134347

SELECTIVE CONVERSION OF 20-METHYLPREGNA- 3,5,20(21)-TRIENE-3,21-DIOL-DIACETATE TO 3-OXO-20-METHYLPREGNA-4,20(21)-DIENE-21- YL-ACETATE ABSTRACT OF THE INVENTION The present invention relates to the conversion of 20- methylpregna-3,5,20(21)-triene-3,21-diol-diacetate to 3-oxo- 20-methylpregna-4,20(21)-diene-21-yl-acetate through the use of a halogenated solvent and a halogenated acid. The benefits of the present invention include a substantial increase in the produation of progesterone via ozonolysis technology.

324033

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