Thiazolidine derivatives and process for their manufacture

Details Thiazolidine derivatives and process for their manufacture Thiazolidine derivatives and process for their manufacture

C - Chemistry, Metallurgy

07

D

260/310.1, 260/3

C07D 277/14 (2006.01) C07D 207/16 (2006.01) C07D 239/10 (2006.01) C07D 277/18 (2006.01) C07D 295/215 (2006.01) C07D 513/04 (2006.01)

Patent

CA 1089472

ABSTRACT OF THE DISCLOSURE This application relates to 4-(sulfamoyl-phenyl)-4- hydroxy-2-iminothiazolidine derivatives having salidiuretic activity of the formula I Image I the tertiary bases thereof and mixtures thereof wherein R1 represents alkyl or alkenyl radicals of 1 to 4 carbon atoms or cycloalkyl radicals of 3 to 6 carbon atoms, R2 and R3 are identical or different and represent alkyl radicals of 1 to 6 carbon atoms, cycloalkyl radicals of 3 to 6 carbon atoms, alkenyl radicals of 3 to 4 carbon atoms, phenylalkyl radicals of 1 to 3 carbon atoms in the alkyl moiety, or a phenyl radical, and in which R1 and R2 may together also represent an alkylene chain of 2 or 3 carbon atoms and/or R2 together with R3 may represent an alkylene chain of 4 to 7 carbon atoms which may be branched and wherein a methylene group may be replaced by an O-atom or a NCH3-group, wherein Y represents hydrogen, bromine or chlorine, R4 represents hydrogen or an alkyl radical of 1 to 4 carbon atoms, R5 is hydrogen, an alkyl radical of 1 to 4 carbon atoms, cycloalkyl of 5 to 7 carbon atoms, benzyl, the aromatic nucleus of which may be substituted by chlorine or methyl, or phenylethyl, and in which R4 together with R5 may also represent an alkylene chain of 4 to 7 carbon atoms which may be branched, and X represents the anion of a pharmacologically tolerated acid. Their preparation is also described.

269714

Affiliated with

Also associated with

Rating

Thiazolidine derivatives and process for their manufacture does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thiazolidine derivatives and process for their manufacture, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thiazolidine derivatives and process for their manufacture will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-471878