Polypeptide agents for blocking the human allergic response

Details Polypeptide agents for blocking the human allergic response Polypeptide agents for blocking the human allergic response

C - Chemistry, Metallurgy

07

K

530/5.04, 530/7.

C07K 16/06 (2006.01) C07K 5/093 (2006.01) C07K 5/103 (2006.01) C07K 14/575 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1087171

POLYPEPTIDE AGENTS FOR BLOCKING THE HUMAN ALLERGIC RESPONSE ABSTRACT OF THE DISCLOSURE A group of relatively low molecular weight polypeptides having from 3 to 10 amino acids block the allergic response. These "blocking" polypeptides have amino acid sequences corresponding to amino acid sequences appearing in the 2nd, 3rd and 4th domains of the epsilon chain of IgE. Specific active "blocking" polypeptides are disclosed and the syn- thesis and use thereof are described.

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