C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/325.1, 260/2
C07D 295/20 (2006.01) C07C 275/38 (2006.01) C07D 295/215 (2006.01) C07D 303/22 (2006.01)
Patent
CA 1061341
ABSTRACT OF THE DISCLOSURE This invention disclosed a new and commercially useful process for the preparation of phenoxypropylamine derivative of the general formula (I): (I) Image and the acid addition salts thereof, wherein, R is a hydrogen atom or an alkyl group, R1 is a hydrogen atom or an alkyl, cycloalkyl, aralkyl or aryl group or R and R1 together represent a divalent, optionally branched hydrocarbon group, optionally sub- stituted, R2 is an alkyl, aralkyl, or aryl group and R3 is an alkyl, hydroxyalkyl, cycloalkyl or cyanalkyl group. This process comprises reacting an alkali metal salt of a phenol of general formula (II) (II) Image with a compound or mixture of compounds of the general formula (III) Image (III) in which X is a group Image or Image and R4 is hydrogen or a group which can be split off hydrogenolytically, and when R4 is hydrogen isolating the product of formula I as either the free base or as the acid addition salt. When R4 is a group which can be split off hydrogenolytically the process further comprises the step of splitting off the group and then isolating the product of formula (I) as either the free base or the acid addition salt.
239398
Chemie Linz Aktiengesellschaft
Na
LandOfFree
Process for the preparation of phenoxypropylamine... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for the preparation of phenoxypropylamine..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of phenoxypropylamine... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-491237