Thioxo-1h-benz(de)isoquinoline-2(3h)- acetic acid derivatives

Details Thioxo-1h-benz(de)isoquinoline-2(3h)- acetic acid derivatives Thioxo-1h-benz(de)isoquinoline-2(3h)- acetic acid derivatives

C - Chemistry, Metallurgy

07

D

260/282.7

C07D 221/14 (2006.01)

Patent

CA 1153766

AHP-7451 ABSTRACT OF THE DISCLOSURE Herein disclosed are 1H-benz[de]isoquinoline-2(3H)-acetic acid derivatives. The derivatives are characterized by being derived from 1,3-dioxo-1H-benz[de]isoquin- oline-2H-acetic acid by replacing one of the oxygen atoms with sulfur and by optional substitution at position 6 with a phenylthio group. The derivatives inhibit lens aldose reductase in a diabetic subject.

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