Stabilized radiographic scanning agents

A - Human Necessities – 61 – K

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A61K 51/12 (2006.01) A61K 51/04 (2006.01)

Patent

CA 1122524

STABILIZED RADIOGRAPHIC SCANNING AGENTS Mahdi Bakir Fawzi ABSTRACT OF THE DISCLOSURE Stable compositions, useful as technetium-99m-based scintigraphic agents, comprise gentisic acid or a pharma- ceutically-acceptable salt or ester thereof in combination with a pertechnetate reducing agent or dissolved in pertechnetate-99m (99mTcO4) solution. The compositions are especially useful in combination with a phosphate or phos- phonate material which carries the radionuclide to bone, thus providing a skeletal imaging agent.

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