Biologically active amides

A - Human Necessities – 61 – K

Patent

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167/103, 167/104

A61K 35/12 (2006.01) A61K 38/22 (2006.01) C07K 5/06 (2006.01)

Patent

CA 1067822

ABSTRACT OF THE DISCLOSURE A polypeptide, other than somatostatin, isolatable from the pancreas of a vertebrate species and effective in lowering the concentration in the blood of glucose and insulin upon administration to hyperglycaemic, hyperinsulinaemic mice of the NZO strain, or a pharmaceutically acceptable salt or metal complex of said polypeptide, useful in effecting a reduction in weight or appetite of a mammal or to treat obesity, hyperglycaemia or hyperinsulinaemic pharmaceutical formulations of said polypeptide and their preparation; and the use of said polypeptide as described hereinabove.

250743

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