Pharmaceutical compositions comprising trimethoprim and...

A - Human Necessities – 61 – K

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A61K 31/505 (2006.01)

Patent

CA 1136047

"Pharmaceutical compositions comprising tripethoprim and N-ethyl- ? - pyridone-3-carboxylic acid derivatives". Abstract of the disclosure Pharmaceutical compositions comprising trimethoprim and a N-ethyl- ? - pyridone-3-carboxylic acid derivative, such as nalidixic, oxolinic or piromidic acid, are more effective than previously known trimethoprim- containing compositions for the treatment of infections affecting the urinary tract . Trimethoprim and the foregoing acid derivatives unpredictably show a noticeable synergistic effect.

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