5-(1,1-diphenyl-3-(4-hydroxy-4-phenylpiperidino)...

Details 5-(1,1-diphenyl-3-(4-hydroxy-4-phenylpiperidino)... 5-(1,1-diphenyl-3-(4-hydroxy-4-phenylpiperidino)...

C - Chemistry, Metallurgy

07

D

260/278.4

C07D 413/10 (2006.01) C07D 211/32 (2006.01) C07D 211/36 (2006.01) C07D 271/10 (2006.01) C07D 453/06 (2006.01) C07D 487/08 (2006.01)

Patent

CA 1067498

ABSTRACT OF THE DISCLOSURE The present invention is concerned with 1,1-diaryl-1-oxadiazol-alkylamines. These compounds are prepared by reacting the tetrazoles of the present invention in the presence of a solvent such as pyridine with a suitable anhydride or acid chloride to give the oxadiazoles. The compounds of the present invention possess potent anti-diarrheal utility as evidenced by their ability to inhibit gastro-intestinal motility. These subject compounds also possess a moderately high degree of analgesia.

223485

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