Dithioacyldihydiopyrazole carboxylic acid derivatives,...

Details Dithioacyldihydiopyrazole carboxylic acid derivatives,... Dithioacyldihydiopyrazole carboxylic acid derivatives,...

C - Chemistry, Metallurgy

07

D

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C07D 207/16 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) C07D 231/06 (2006.01) C07D 403/12 (2006.01)

Patent

CA 1155445

Abstract Abstract of the Disclosure Compounds having the formula Image and Image wherein: R1 is hydrogen, alkyl, aryl or arylalkyl: R2 is hydrogen and R3 is hydrogen, hydroxy, alkoxy or halogen, or together R2 and R3 can be =O or -X-(CH2)t-X- wherein X is oxygen or sulfur and t is 2 or 3; R4 is hydrogen or alkyl; R5 is hydrogen, alkyl or trifluoromethyl: R6 is alkyl of 1 to 20 carbon atoms, aryl, arylalkyl or a 5- or 6-membered heterocyclic group having 1 or 2 nitrogen, sulfur or oxygen atoms in the ring; R7 is aryl; m is 0, 1 or 2; and n is 1 or 2 have useful hypotensive activity.

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