Osmotically driven active agent dispenser and process for...

Details Osmotically driven active agent dispenser and process for... Osmotically driven active agent dispenser and process for...

A - Human Necessities

61

M

128/104

A61M 35/00 (2006.01) A61K 9/00 (2006.01)

Patent

CA 1092469

TITLE: OSMOTICALLY DRIVEN ACTIVE AGENT DISPENSER AND PROCESS FOR MAKING SAME ABSTRACT OF THE DISCLOSURE An osmotically driven dispenser for releasing active agents, such as drugs, to liquid-containing environments, such as various body sites. The dispenser comprises a housing made from a semipermeable material, a flexible partition that divides the housing interior into two compartments, an initially nonflowable, osmotically effective active agent composition filling one of the compartments, an osmotically effective com- position filling the other compartment, and an outlet passageway extending through the housing to the active agent-containing compartment. In operation liquid is imbibed from the environ- ment through the housing into both compartments, thereby con- verting the active agent composition to a flowable form and causing the flexible partition to displace into the active agent-containing compartment and force active agent therefrom via the outlet passageway. The release rate of active agent from the dispenser is a function of the combined rate of liquid influx into both compartments.

291085

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