Process for producing novel pyrazole derivatives

C - Chemistry – Metallurgy – 07 – D

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260/315.3, 260/2

C07D 403/12 (2006.01) C07D 231/12 (2006.01) C07D 241/24 (2006.01)

Patent

CA 1050549

ABSTRACT OF THE DISCLOSURE A process for the preparation of a compound of the general formula [II], Image [II] (in which R represents 2-acetaminoathyl, 2-ethyoxycarbonyl-aminoethyl, 2-(2-methoxy-5-chlorobenzoylamino)ethyl, 2-(2-pyrazinecarbonylamino)ethyl, isobutyl, cyclohexyl group or chlorine atom; n is 0 or 1 when R1 represents hydrogen atom; n is 0 when R1 represents methyl, phenyl, or benzyl group) by the reaction of a compound of the general formula [I], Image [I] (in which R, R1, and n representation are the same as above) and acetylacetone. The novel compounds of formula [II] are very useful as antidiabetic agents.

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