Process for the preparation of new fluorophenacyl- amine...

C - Chemistry – Metallurgy – 07 – C

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260/604, 260/579

C07C 91/16 (1980.01) C07C 97/10 (1980.01)

Patent

CA 1142964

ABSTRACT OF THE DISCLOSURE The present invention relates to new com- pounds belonging to the family of fluorophenacyl-amine derivatives of formula : Image (I) [wherein A is CO or CHOH and R is CH(CH3)2 or C(CH3)3-] and selected from the group consisting of N-(4-fluoro- phenacyl)-isopropylamine, N-(2-fluorophenacyl)-tertio- butylamine, 1-(2-fluorophenyl)-2-tertiobutylamino- 1-ethanol, 1-(4-fluorophenyl)-2-tertiobutylamino-1- ethanol, and their addition salts. These new derivatives are useful in therapeutics, particularly as sedative agents, CNS- antidepressants and antiaggressive agents.

374846

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