Spermicidal vaginal composition comprising...

A - Human Necessities – 61 – K

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167/234

A61K 31/425 (2006.01)

Patent

CA 1060345

"SPERMICIDAL VAGINAL COMPOSITIONS COMPRISING 1,2-BENZISOTHIAZOLE DERIVATIVES" Abstract Or the disclosure A spermicidal vaginal composition comprises a spermi- cidal-effective amount of a 1,2-benzisothiazole derivative having the general formula (I) Image wherein: X is either O or S; y is H; NO2; an halogen atom or an alkyl radical having from 1 to 4 carbon atoms; and R is H; a straight or branched alkyl or alkenyl radical having from 1 to 6 carbon atoms, optionally substituted by one or more hydroxyl, tertiary amino and alkoxyl groups;, a cycloaliphatic radical having from 3 to 8 carbon atoms; an alkyl radical optionally substituted by halogen atoms, alkyl or alkoxyl radicals; an aralkyl radical optionally having the aromatic moiety substituted by halogen atoms, alkyl and alkoxyl radicals; or an acyl radical -COR' wherein R' is an alkyl group having from 1 to 4 carbon atoms or an aryl radical. - 1 -

256023

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