Process of producing novel macrolactone derivatives

Details Process of producing novel macrolactone derivatives Process of producing novel macrolactone derivatives

C - Chemistry, Metallurgy

07

D

260/230, 260/355

C07D 313/00 (2006.01) C07D 407/06 (2006.01) C07D 493/04 (2006.01) C07H 15/04 (2006.01) C07H 17/08 (2006.01)

Patent

CA 1119588

PROCESS OF PRODUCING NOVEL MACROLACTONE DERIVATIVES ABSTRACT By protecting the aldehyde group of a macrolide series anti- biotics with a cyclic acetal or thioacetal, novel macrolide deri- vatives can be produced from the macrolide series antibiotics by releasing successively the sugar moieties bonded to the macrolide antibiotics. The novel macrolide derivative obtained by this invention, that is, the derivatives of a macrolide series antibiotics produ- ced by releasing partially or wholly the sugar moieties bonded are useful as intermediates for producing novel macrolide series anti- biotics.

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