Pharmaceutical heterocyclic comounds, preparation, use and...

C - Chemistry – Metallurgy – 07 – D

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C07D 403/06 (2006.01) C07D 209/86 (2006.01) C07D 295/067 (2006.01) C07D 295/088 (2006.01)

Patent

CA 1141384

PHARMACEUTICAL HETEROCYCLIC COMPOUNDS, PREPARATION, USE AND INTERMEDIATES THEREFOR AND THEIR PREPARATION ABSTRACT This invention is directed to the compound 9-[3- (3,5-cis-dimethylpiperazino)propy]carbazole, salts thereof and solvates of the salts which are useful in treating aggression and/or psychoses in man and also in treating aggression in animals such as dogs, swine, horses and cattle. The invention is also directed to methods for the preparation of the carbazole, salts and solvates, to pharmaceutical compositions containing them, the preparation of such compositions and the use of the carbazole, salts and solvates in human and veterinary medicine. Also provided by the invention are intermediates of value in the preparation of the carbazole, salts and solvates by the methods described.

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