Pyrimidoquinoxaline derivatives, process for producing the...

Details Pyrimidoquinoxaline derivatives, process for producing the... Pyrimidoquinoxaline derivatives, process for producing the...

C - Chemistry, Metallurgy

07

D

260/242.1

C07D 487/04 (2006.01) C07D 241/44 (2006.01) C07D 475/14 (2006.01) C07D 491/14 (2006.01)

Patent

CA 1083147

ABSTRACT OF THE DISCLOSURE Substituted pyrimido[5,6-b]quinoxaline-4(3H)-one-2- carboxylic acid compounds represented by the formula Image (I) wherein: R designates a member selected from the group consisting of hydrogen, alkyl groups having 1 to 4 carbon atoms, benzyl group, and phenyl group; and each of R1, R2, R3 and R4 independently designates a member selected from the group consisting of hydrogen, alkyl group having 1 to 4 carbon atoms, alkoxy groups having 1 to 4 carbon atoms, halogens, benzyloxy group, hydroxyl group, alkyl-thio groups having 1 to 4 carbon atoms, and alkylenedioxy groups having 1 to 4 carbon atoms and formed by the bonding of two of R1, R2, R3 and R4, or pharmacologically acceptable salts of said compounds. The compounds of the invention are suitable for oral administration in the treatment of allergic asthma.

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