Mixtures of 1,3-bis(2-carboxy-chromon-5-yloxy) propan- 2-ol...

A - Human Necessities – 61 – K

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A61K 31/335 (2006.01) A61K 31/395 (2006.01) A61K 31/435 (2006.01) C07D 213/38 (2006.01) C07D 311/22 (2006.01)

Patent

CA 1113862

ABSTRACT There are described salts id 1,3-bis(2-carboxychromon-5- yloxy)propan-2-ol with a basic compound which has anti-histamine H1 receptor antagonist properties and which contains a 6 membered nitrogen heterocyclic ring, and pharmaceutical compositions comprising (a) one or more of 1,3-bis(2-carboxychromon-5-yloxy)propan-2-ol, or a pharmaceutically acceptable salt thereof, in combination with (b) one or more anti-histamines having H1 receptor antagonist properties, and which contains a 6 membered nitrogen heterocyclic ring. There are also described methods of making the salts and composition, packages containing them and methods for their use, e.g. as anti-allergic agents.

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