Method of indicating rheumatoid factors

G - Physics – 01 – N

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150/11

G01N 33/48 (2006.01) G01N 33/564 (2006.01)

Patent

CA 1076937

ABSTRACT OF THE DISCLOSURE A method of indicating rheumatoid factors belonging to at least one of the immunoglobulin classes IgM, IgG and IgA in an aqueous sample is disclosed. According to this method any complement factor C1q present in the sample is pacified in a manner known per se, whereafter the sample is reacted with soluble, aggregated immunoglobulin labelled with one or more analytically indicatable atoms or groups to form aggregates between rheumatoid factors and the aggregated, labelled immunoglobulin, said aggregate being precipitated out, where- after the precipitate is separated and the analytically indicatable atoms or groups are indicated in the precipitation phase and/or in the solution. - 2 -

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