Antitumoral composition and its process of preparation

A - Human Necessities – 61 – K

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A61K 31/135 (2006.01) A61K 33/22 (2006.01)

Patent

CA 1142855

ABSTRACT OF THE DISCLOSURE: Antitumoral medicinal composition obtained by dissolving the crystallized boric acid in 800 ml of sodium chloride solution 8,5-9°/00, whereby 2 ml of 4-amino-benzoyl- diethylamino-ethanol chlorhydrate, solution 8% and 10 ml ascorbic acid, solution 10% are added; then distilled water is added up to 1000 ml; the resulting solution is heated at 100°C, for 20 to 60 minutes, sterilized and filtered; the final pH is 5 to 6. The weight ratio between 4-amino-benzoyldiethylamino- ethanol-chlorhydrate, boric acid and ascorbic acid is: 1 : (0,62-1,9) : 6,25. 1 to 5 ml product shall be administered daily, for 20 days, by intravenous route, drop by drop, at intervals of 5 to 6 seconds between the drops; the cycle of 20 administrations shall be repeated 3 to 5 times at intervals of 5 to 10 days.

354516

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