Solid steroid composition and process for preparation

Details Solid steroid composition and process for preparation Solid steroid composition and process for preparation

A - Human Necessities

61

K

167/191

A61K 31/58 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/565 (2006.01) C07D 311/58 (2006.01)

Patent

CA 1082598

ABSTRACT OF THE DISCLOSURE A pharmaceutical composition comprising from 5 to 80 percent by weight of a pharmaceutically active steroid, 1 to 8 percent by weight of sodium starch glycolate and the remainder conventional excipients is prepared by wet granulating the steroid with conventional excipients, drying the granulation until it contains less than 1 percent of water, and blending the granulation with a mixture of the sodium starch glycolate and conventional excipients. A preferred specific embodiment is a capsule blend containing 4,4,17-trimethylandrosta-2,5-dieno[2,3-dlisoxazole.

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