Process for preparing insulin esters

Details Process for preparing insulin esters Process for preparing insulin esters

C - Chemistry, Metallurgy

12

P

195/128.2, 167/1

C12P 21/04 (2006.01) C07K 14/62 (2006.01) C08H 1/00 (2006.01)

Patent

CA 1162868

ABSTRACT Insulin and insulin-like compounds from certain species can in the presence of an L- threonine ester, water, a water miscible organic solvent, and trypsin be transpeptidized into a threonineB30 ester of human insulin in which the protecting group(s) can be removed whereby human insulin is formed.

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