Processes for the production of 3',4'- dideoxykanamycinb

C - Chemistry – Metallurgy – 07 – H

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C07H 15/22 (2006.01) C07H 15/236 (2006.01)

Patent

CA 1095903

TITLE OF INVENTION New processes for the production of 3', 4'- dideoxykanamycin B ABSTRACT OF THE DISCLOSURE A clinically valuable antibiotic, 3', 4'- dideoxykanamycin B is now produced by a reduced number of consecutive steps in an improved overall yield by new processes starting from kanamycin B via intermediate derivatives of kanamycin B in which all the five amino groups are protected with an unsubsti- tuted or substituted benzyloxycarbonyl group and possibly the 2"-hydroxyl group may be protected with a lower alkylsufonyl, arylsulfonyl or aralkyl- sulfonyl group. - 1 -

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