N-substituted-7,8-dihydroxycyclopentano(f)-1,2,3,4-tetrahydr...

Details N-substituted-7,8-dihydroxycyclopentano(f)-1,2,3,4-tetrahydr... N-substituted-7,8-dihydroxycyclopentano(f)-1,2,3,4-tetrahydr...

C - Chemistry, Metallurgy

07

D

260/281.7

C07D 221/16 (2006.01) C07C 45/51 (2006.01) C07C 47/575 (2006.01)

Patent

CA 1061791

Abstract of the Disclosure N-substituted cyclopentano[f]-1,2,3,4-tetrahydro- isoquinolines of the formula Image wherein R1 and R2 represent hydroxy, lower alkoxy, lower alkanoyloxy or aryl-lower alkanoyl groups, R3 represents hydrogen or a lower alkyl group and R4 represents a lower alkyl, arylcarbonyl, aryl-lower alkyl, benzhydryl-lower alkyl, lower alkanoyl, aryl-lower alkanoyl, benzhydryl- lower alkanoyl or benzhydrylcarbonyl group, and acid addition salts and quaternary ammonium salts thereof, and pharmaceutical compositions containing one or more of the compounds useful for lowering blood pressure in animals.

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