2-amino-cyclopent-1-ene-1-dithiocarboxylic acid derivatives...

C - Chemistry – Metallurgy – 07 – C

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260/506.8

C07C 153/043 (1980.01)

Patent

CA 1106397

ABSTRACT OF THE DISCLOSURE New 2-amino-cyclopent-1-ene-1-dithiocarboxylic acid derivatives of the general formula /I/, Image /I/ wherein R is a C2-4 alkenyl group, a C3-8 cycloalkyl group, phenyl group or a C1-6 alkyl group having optionally a C1-4 alkoxy, hydroxy, carboxy and/or amino substituent, with the proviso that if R is an unsubstituted alkyl group, this group contains at least 5 carbon atoms, are prepared by reacting 2-amino-cyclopent-1-ene-1-dithiocarboxylic acid or a salt thereof with an amine of the general formula /II/, R-NH2 /II/ wherein R is as defined above. The new compounds of the invention exert dopamine-.beta.-hydroxylase inhibiting effects.

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