Vinyl polymerisate latex particles bonded to immunological...

G - Physics – 01 – N

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G01N 33/543 (2006.01) G01N 33/48 (2006.01) G01N 33/53 (2006.01) G01N 33/72 (2006.01) G01N 33/80 (2006.01) G01N 33/86 (2006.01) G01N 33/96 (2006.01)

Patent

CA 1103153

ABSTRACT This invention relates to a water-insoluble reagent for an immunologlcal determination having a specific weight corresponding to about that of water in tbe form of discrete latex particles, to which is bound an immuno- logically active material, wherein the latex consists of a dispersion of particles of vinyl polynerisates, which carry the end-groups groups of the formula Image whereby the particles are formed from a core of vinyl and/or diene polymerisate, which carries carboxyl and/or sulphonate functions, and of an outer layer of vinyl polymerisate, which carries as the end-groups groups of the formula Image , and have an average diameter between 0.03 µm and 5 µm.

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